Abiraterone Plus Leuprolide Offers Edge in M0 Hormone-Naive Prostate Cancer

Abiraterone Plus Leuprolide Offers Edge in M0 Hormone-Naive Prostate Cancer

Abiraterone Plus Leuprolide Offers Edge in M0 Hormone-Naive Prostate Cancer

Immunotherapy, which personalizes treatment based on the genetic make-up of tumors, is only successful for a minority of patients, professor Paul Workman, chief executive of the ICR, said in a statement. About 164,690 men are diagnosed of the disease per year.

"Today I'm effectively cancer-free".

Prostate cancer patients with weeks or months to live could survive longer after undergoing immunotherapy treatment, a major trial has shown.

"We were astonished when scans showed that the tumor had become undetectable".

Such patients had experienced "an awesome response", he said.

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Scores of men with the most lethal form of prostate cancer have been "brought back from the brink of death" by a drug found to work where all others have failed in a groundbreaking British-led trial.

Professor Johann de Bono, director of the drug development unit, said that the results of the trail are a "big deal" and "spectacular" as the men who were a part of the study had gone through all possible treatments and were dying, with just a few weeks or months to live but the drug resulted in their cancer shrinking and disappearing, with just minimal cancer left.

That is not unusual for immunotherapy.

If patients who can respond to immunotherapy are identified, some of them may be able to avoid treatments that come with unwanted side effects.

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Nell Barrie, from Cancer Research UK, said: "The next step will be to find out how to tell which men will benefit from taking this drug".

"It's exciting that immunotherapy could offer some men more time with their loved ones where they have such advanced disease that they have run out of existing treatment options".

Immunotherapy drugs work by stimulating the body's immune system so it can recognise and fight cancer.

The recent study with a drug named pembrolizumab was worked out with those who are at the very advanced stage of the prostate cancer.

The researchers suggest these mutating cancer cells may be easy for the immune system to recognise and attack because they look different from healthy cells.

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Eight months of treatment with abiraterone (AA) plus leuprolide for biochemically recurrent non-metastatic hormone-naive prostate cancer (M0HNPC) improves PSA-free survival compared with the use of leuprolide alone, with no delay in testosterone recovery or significant safety concerns, according to data presented at the 2018 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago, Illinois, on Monday, June 4.

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