Most Women with Early Breast Cancer Do Not Benefit From Chemotherapy

Most Women with Early Breast Cancer Do Not Benefit From Chemotherapy

Most Women with Early Breast Cancer Do Not Benefit From Chemotherapy

The study found that for women with hormone receptor (HR)-positive, HER2-negative, axillary lymph node-negative breast cancer, treatment with chemotherapy and hormone therapy after surgery is not more beneficial than treatment with hormone therapy alone.

The findings suggest that thousands of women could one day forgo a treatment with long-term health ramifications without risking the spread of cancer.

Cancer care has been evolving away from chemotherapy - older drugs with harsh side effects - in favor of gene-targeting therapies, hormone blockers and immune system treatments.

At MedShadow, she reports on new findings and research on the side effects of prescription drugs.

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Carolina's Lineberger Comprehensive Cancer Center, said she'd be quite comfortable counseling patients to bypass chemo if they had been like those from the study who didn't gain from it. "Any woman with early-stage breast cancer age 75 or younger should have the 21-gene expression test and discuss the results with her doctor to guide her decision to the right therapy".

"Until now, we've been able to recommend treatment for women with these cancers at high and low risk of recurrence, but women at intermediate risk have been uncertain about the appropriate strategy to take", said Jeffrey Abrams, M.D., associate director of NCI's Cancer Therapy Evaluation Program. Moore said the "OncoType DX" test has always been used to spare many women with "low risk" scores from chemotherapy treatments.

The study was supported in part by the Breast Cancer Research Foundation, Komen Foundation, and the Breast Cancer Research Stamp.

Jane Murphy, clinical nurse specialist at Breast Cancer Care, said: "It's really interesting to see different avenues are being explored to help women adapt to life after breast cancer, which can be incredibly daunting and hard". The money was used to pay for the gene test, which costs more than $4,000 per person.

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The study was extensive so patients who fit in this new category should be very confident with their course of treatment, even if it's without chemotherapy.

"Testing solved a large issue of figuring out that desires chemo, said Lots of women believe" if I do not get chemotherapy I will die, and when I get chemo I'm likely to be treated", but the results show there is a sliding scale of advantage and sometimes not one, " he explained.

Adine Usher, 78, who lives in Hartsdale, New York, joined the study 10 years ago at Montefiore and was randomly assigned to the group given chemo. "I'm a firm believer in medical research".

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