Co-Testing for Cervical Cancer is Best, But Not Perfect

Co-Testing for Cervical Cancer is Best, But Not Perfect

Co-Testing for Cervical Cancer is Best, But Not Perfect

Out of the subjects who examined negative in the HPV test, just twenty-two had abnormal cells, whereas out of those who tested negative in the Pap smear, fifty-two women had abnormal cells. According to the article, the study compared the HPV test with traditional Pap smear screening among 19,000 Canadian women over 4 years. These HPV viruses are sexually transmitted and can cause most of the anal cancers; many vulvar, vaginal and penile cancers; and some oropharyngeal cancers as well along with the cervical cancers.

The research came from doctors and scientists working on Canada's cervical screening programme, including researchers from the University of British Columbia, British Columbia Centre for Disease Control, Lower Mainland Laboratories, British Columbia Cancer and McGill University.

The findings were published July 3 in the Journal of the American Medical Association. While neither method was foolproof, the study found that women who originally had the Pap smear were more than twice as likely to have abnormal cells, the article reported. The vaccine is given to teens and young adults, but generations of women are still at risk of cervical cancer because HPV eventually infects most people at some point. HPV tests are also referred HPV DNA tests, which is mainly a follow up test for the abnormalities detected during the Pap smear tests.

"In our world this study is going to be a pretty big deal, in a good way", says Dr. Kathleen Schmeler, a gynecologic oncologist at the University of Texas MD Anderson Cancer Center.

Trump calls Statue of Liberty climber a clown
A protester is seen on the Statue of Liberty in New York , New York, US, July 4, 2018 in this picture obtained from social media. Police officers were tethered to the statue, and after a brief standoff, they lowered Okoumou to safety.

The coverage in the Mail Online was accurate but failed to explain that one possible risk of changing to the new system would be an increase in "false positive" results, where women with HPV but no cancerous changes are referred for further investigations.

The HPV test was more likely to pick up pre-cancerous cervical lesions earlier in the study, so the women in this group were significantly less likely to develop invasive neoplasia, or cervical cancer. Despite the widespread use of cervical cancer screening with a Pap smear, it was estimated that approximately 12,820 women in the United States would develop, and 4210 would die, from cervical cancer in 2017.

Testing for HPV is a less intrusive method for cancer screening.

Several experts predicted the results would spur efforts to entirely replace the Pap test with the HPV test.

Pruitt Was Told to Resign in Call From White House
Scott Pruitt , President Donald Trump's beleaguered Environmental Protection Agency administrator, resigned Thursday , the president announced on Twitter.

They also cautioned that more work needs to be done to assess the economic consequences of changing the screening model.

Currently, the US Preventive Services Task Force recommends women aged 30-65 receive both a Pap and HPV testing every five years. "Even if we could magically vaccinate 100 percent today, it would take 30 years for them to reach the age of 40, and to see a meaningful decrease in cervical cancer", Spitzer added. But there were still no final guidelines issued on this and that's why the new study might be important in helping with the decision.

Researchers in the study said one of the next steps is to look into whether the additional cases of cervical cancer that could be found with HPV testing would justify the cost of co-testing - or whether HPV testing alone would be more cost effective. He called use of the HPV test only a "reasonable strategy" but noted that the test's strength - its sensitivity - could result in more positive results and more testing. But others disagree, saying that the Pap smear can catch a small number of cases of abnormal cells that might be missed by the HPV test and that co-testing should continue.

More women were referred for colposcopy after HPV tests at the start of the study: 57 per 1,000 women compared with 30.8 per 1,000 women after smear tests - but the reverse was true at 48 months. Partly because of that, he said, "we're a long way away from replacing the Pap smear".

Courtois says he never mocked England 'keeper Pickford's height
As for my own penalty, I just went through the process that I normally do, that I've been working on. There were scenes of jubilation and shock across Carlisle as England rewrote history last night.

Related news