New Inexpensive Test Can Detect Cancer Within 10 Minutes

New Inexpensive Test Can Detect Cancer Within 10 Minutes

New Inexpensive Test Can Detect Cancer Within 10 Minutes

Scientists have developed a universal cancer test that can detect traces of the disease in a patient's bloodstream.

The test uses a color-changing fluid to identify the presence of malignant cells anywhere in the body, providing results in 10 minutes.

"We believe that this simple approach would potentially be a better alternative to the current techniques for cancer detection". In some cases, the accuracy of cancer detection runs as high as 90%. They further claimed that this test is likely to make cancer diagnosis more accessible and affordable.

At this stage, the test indicates only whether someone has cancer, but can not tell the type of cancer they have or how advanced it is.

Researchers have always been looking for a commonality among cancers to develop a diagnostic tool that could apply across all types.

Scientists have developed a cheap and simple test that can detect malignancy in 10 minutes.

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When separating from the blood in the given solution, the cancer cells form three-dimensional patterns that are easily observed, the researchers said.

Sina said: "It works for tissue-derived genomic DNA and blood-derived circulating free DNA".

The team noticed that in cancer cells, methyl groups were clustered at certain positions on the genome - a stark contrast to healthy cells where the groups are dispersed throughout.

The researchers were surprised to find the marker appeared in every type of breast cancer they examined, as well as in people with prostate cancer, colorectal cancer and lymphoma.

Cancer alters the DNA of healthy cells, particularly in the distribution of molecules known as methyl groups, and the test detects this altered patterning when placed in a solution such as water.

Methyl groups are spread across the genome, but the AIBN team found that cancer cells' genomes often lack methyl groups except for "intense clusters of methyl groups at very specific locations".

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Cancer is the second leading cause of death globally, and is responsible for an estimated 9.6 million deaths in 2018, according to estimates from the World Health Organisation (WHO).

In the lab, gold particles are commonly used to help detect biological molecules (such as DNA).

The quick and simple test sees DNA extracted from a tissue sample before it is mixed with water, to which gold nanoparticles are added.

"We designed a simple test using gold nanoparticles that instantly change colour to determine if the 3D nanostructures of cancer DNA are present", said Matt Trau, a professor at the University of Queensland.

Dr Ged Brady, from the Cancer Research UK Manchester Institute, said: 'Further clinical studies are required to evaluate the full clinic potential of the method'.

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